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Primperan amp 10 mg /kg per day) and a control group of non-injected, untreated rats. Rats were tested for locomotion, exploratory activity and open field activity. All the animals were also tested for their general behavioral and biochemical parameters, including serum levels of glucocorticoid (CORT) (1.0–3.0 mg/ml) and Diazepam 5mg 90 pills US$ 290.00 US$ 3.22 testosterone (T) (1.0–5.6 mIU/ml); serum levels of thyroid hormones (T4 (20.6 μg/ml), T3 (14.8 and TSH (0.2 μg/ml); serum concentrations of corticosterone (CORT) (0–16.3 μmol/l), cortisol (0–0.5 μmol/l) and thyroid hormones (CORT, T3, TSH); urinary catecholamines (ADH, DHEA, DHT) (0–0.3–0.5 μmol/ml); and urine 5-hydroxyindoleacetic acid (5-HIAA) (0.3–0.7 mg/dl). RESULTS: Corticosterone (CORT) levels in control rats were significantly higher (p<0.05) than the levels obtained in our previous study. Cortisol-induced reduction of locomotion was significantly higher (p<0.05) in rats receiving amphetamine (10 mg/kg per day) than in rats receiving vehicle (control). These effects were accompanied by reduced exploratory activity in both amphetamine and control rats. Administration of amphetamine (10 mg/kg per day) or corticosterone (1.0–3.0 mg/ml) increased Is diazepam generic for valium the levels of serum T (1.0–3.0 mIU/l) and decreased the levels of serum T3 (1.0–3.0 μg/ml). In all cases, this decrease was accompanied by an increase in adrenal CORT (p<0.01). Cortisol-induced reduction of exploratory activity was greater (p<0.01) in rats receiving amphetamine or corticosterone than in Buy cheap ultram online vehicle-treated rats. Amphetamine (10 mg/kg per day) or corticosterone (1.0–3.0 mg/ml) also increased the levels of urinary DHEA (1.2–5.6 mIU/l) and cortisol (0.4–1.2 μmol/l) by about 40% and 50%, respectively. CONCLUSION: These results reveal that amphetamine or corticosterone increase locomotor activity in rats. The increase locomotion and reduction in exploratory activity are accompanied by elevations in serum T and decreases T3, T4, TSH, cortisol and DHEA. This may be due to increased Alprazolam buy online cheap adrenal CORT or the effects of corticosterone on corticotropin-releasing factor (CRF) production in the adrenal cortex.

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