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Cialis generic safety profile is generally considered to be excellent, although the drug is known to occasionally produce serious side effects in some patients. In a clinical study of more than 5,000 women, Bayer's Viibryd (bexarotene), a prescription drug used to treat psoriasis, showed an 85 percent success rate, or a 75 percent reduction in the patients' skin lesions compared to a placebo, according January press release. Bayer, the largest generic pharmaceutical manufacturer in the country, is also looking at new ways to treat skin conditions such as rosacea and psoriasis. Some of the new products target proteins that are altered by the ultraviolet rays from sunlight or sunlight-damaged skin that are damaging cells. In the next few years, company plans to introduce several new topical medicines and creams that target skin diseases. "The skin is a sensitive organ and therefore we are constantly looking for new opportunities to improve treatment," said Bayer CEO Werner Baumann, who also chairs the board of skin diseases association. "These new medications may be targeted towards different skin types." Bayer shares closed Monday at $115.50 - $8.85 a share. In the United States, top 10 generic drug companies control approximately 60 percent of the market adderall for sale in uk share, according to Association for Marketing and Research in Drug Sales. That number has decreased over time, though, and in 2017, the top 10 firms controlled just over half of the country's total. That said, there are some companies that have shown promise when it comes to developing generic drugs. Drugmakers such as AstraZeneca and Shire have spent years developing new generic versions of older drugs, but that hasn't always been a success. Shire has come up with several drugs that have failed to reach the market, including its long-awaited and controversial generic version of Soliris, an arthritis medication. The generic drug has a lower price, but received mixed reviews. Also worth noting is the fact that a growing number of pharmaceutical companies are looking into developing new medicines. According to the New Yorker, about 20 percent of the top 200-plus drugs in United States are now being developed or patented by the pharmaceutical industry. New Yorker also reports that the number of generics is expected to double within a decade, from about 1 to 7 products in 2013 about 14 by 2021. "The U.S. has become a very large, attractive market," said Mark O'Connell, a former president of the Pharmaceutical Research and Manufacturers of America, or PhRMA, who now works in drug safety at the Johns Hopkins Bloomberg School of Public Health. "It's a pretty stable market, with lot of opportunities for innovative drug discovery." Still, it's worth understanding that generic drugs don't always cost less than brand-name drugs. In some cases, generic drugs are more expensive than the brand version, which is why some patients might switch medications. "Sometimes, patients prefer the generic version because it works just as well," said Lisa T. Johnson, an associate professor adderall xr buy uk of medicine at Harvard Medical School. "They may not consider switching." Some of the biggest players in generics game today include: Allergan, Pfizer, Merck, Novartis, Shire, AstraZeneca, GlaxoSmithKline, Eisai, GSK and Bristol-Myers Squibb. In 2017, the pharmaceutical and medical device industries have seen overall sales grow by 5 percent, according to data released earlier this month from Closest thing to tramadol over the counter IMS Health. There's a huge amount of research and investment dollars that go into developing new drugs, and the pharmaceutical industry has been able to increase its share of the market over last decade. But generic drug research and development has not always been so successful. In fact, as the New Yorker reported, average drug that is launched each year a older than the one in 2007. According to the report, average drug in U.S. has more than doubled in price since 1999. Still, Johnson said it's encouraging to see the pharmaceutical industry continuing to develop drugs. "We still need the pharmaceutical industry to come up with new medicines," she said. The FDA does keep a lookout for issues involving drug shortages, but has not found any major shortages as of yet. And if the industry continues to develop drugs for new uses, Johnson said it could be possible "one day" for the FDA to make that happen. "The future of generic drugs is very exciting," she said.

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